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Pesticide License Education

3 Major Classes of Biopesticides and Their Advantages

According to the EPA, Biopesticides are naturally occurring substances that control pests.
These substances fall into three major classes:


  1. Biochemical pesticides are naturally occurring substances that control pests by non-toxic mechanisms. Conventional pesticides, by contrast, are generally synthetic materials that directly kill or inactivate the pest. Biochemical pesticides include substances that interfere with mating, such as insect sex pheromones, as well as various scented plant extracts that attract insect pests to traps. Because it is sometimes difficult to determine whether a substance meets the criteria for classification as a biochemical pesticide, EPA has established a special committee to make such decisions.
  2. Microbial pesticides consist of a microorganism (e.g., a bacterium, fungus, virus or protozoan) as the active ingredient. Microbial pesticides can control many different kinds of pests, although each separate active ingredient is relatively specific for its target pest[s]. For example, there are fungi that control certain weeds and other fungi that kill specific insects.
    The most widely used microbial pesticides are subspecies and strains of Bacillus thuringiensis, or Bt. Each strain of this bacterium produces a different mix of proteins and specifically kills one or a few related species of insect larvae. While some Bt ingredients control moth larvae found on plants, other Bt ingredients are specific for larvae of flies and mosquitoes. The target insect species are determined by whether the particular Bt produces a protein that can bind to a larval gut receptor, thereby causing the insect larvae to starve.
  3. Plant-Incorporated-Protectants (PIPs) are pesticidal substances that plants produce from genetic material that has been added to the plant. For example, scientists can take the gene for the Bt pesticidal protein and introduce the gene into the plant's own genetic material. Then the plant, instead of the Bt bacterium, manufactures the substance that destroys the pest. The protein and its genetic material, but not the plant itself, are regulated by EPA.


There are advantages to using biopesticides in that they are less toxic than conventional pesticides and generally affect only the target pest and closely related organisms.  In contrast, the use of conventional pesticides has been known to adversely affect other organisms such has insects, mammals and birds. Biopesticides are often effective in very small quantities and decompose quickly which results in lower exposures and an avoidance of pollution problems. They can often be used as a component of Integrated Pest Management (IPM) programs, and can greatly reduce the use of conventional pesticides, yet still produce a high crop yield.

In 1994, the EPA established the Biopesticides and Pollution Prevention Division in the Office of Pesticide Programs to facilitate the registration of biopesticides. This division promotes the use of safer pesticides, including biopesticides, as components of IPM programs. The division also coordinates the Pesticide Environmental Stewardship Program (PESP).

Since biopesticides tend to pose fewer risks than conventional pesticides, EPA generally requires much less data to register a biopesticide than to register a conventional pesticide. In fact, new biopesticides are often registered in less than a year, compared with an average of more than three years for conventional pesticides.

For more information on this subject and more, you may contact

Ombudsman, Biopesticides and Pollution Prevention Division (7511P)
Office of Pesticide Programs
Environmental Protection Agency
1200 Pennsylvania Avenue, NW
Washington, D.C. 20460

(source: EPA.GOV)

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